.boxPanel_container {
  background-color: var(--background-color);
}

.standardPanel_content hr {
  border-top: 0.1875em solid var(--color-red-30);
  width: 100%;
  display: inline-block;
  margin: 10px 0px 0px;
}

.dosing .dosePanels_wrapper .dosePanel_box.box-6 {
  background-color: initial;
}
.standardPanel_content :where(h1) {
  margin-bottom: 0;
}

.anchor_anchor__LcM38 {
  scroll-margin-top: var(--scroll-margin);
  display: block;
}

.custom-list {
  margin-left: 0;
}

.sm-d-flex {
  font-size: 13px;
}

.h4-trastuzumab {
  position: relative;
  top: 8px;
}

.tukysa-sup {
  font-size: 22px;
  position: relative;
  top: 4px;
  left: -1px;
  font-weight: 500;
}

.h4-margin-bottom {
  margin-bottom: 10px;
}

.text-blue {
  color: var(--color-blue-60);
}

.bullet-list {
  margin-left: 20px;
}

.scroll-margin-anchor {
  scroll-margin-top: 273.25px;
}

.boxPanel_btnWrap {
  padding-top: 1em;
  display: flex;
  flex-direction: column;
  gap: 1em;
}

.boxPanel_btn {
  font-weight: var(--font-weight-semibold);
  width: 100%;
}

.boxPanel_iconBtn {
  display: flex;
  flex-direction: row-reverse;
  align-items: center;
  gap: 0.5em;
}

.boxPanel_iconBtn .boxPanel_icon {
  fill: var(--color-white);
  height: 0.875em;
  max-width: 0.875em;
  min-width: 0.875em;
  width: 100%;
}

.boxPanel_iconBtn:hover .boxPanel_icon {
  fill: var(--color-white);
}

.boxPanel_inner {
  padding: var(--padding);
}

.boxPanel_content {
  max-width: 60em;
  width: 100%;
}

.boxPanel_content:where(h1, h2, h3, h4, h5, h6) {
  margin-bottom: 0.5em;
  font-weight: var(--font-weight-medium);
  color: var(--color-blue-60);
  font-size: 1.125em;
}

.boxPanel_content hr {
  overflow: visible;
  border-top: 1px solid var(--color-teal-50);
  position: relative;
  width: calc(100% + var(--line-width));
  margin: 1.5em 0px;
}

.boxPanel_content hr::before {
  position: absolute;
  background-color: var(--color-teal-50);
  content: "";
  height: 0.625em;
  width: 0.625em;
  bottom: 0.3125em;
  left: -0.0625em;
  top: -0.3125em;
}

.boxPanel_content ul {
  margin-left: 1.25em;
}

.boxPanel_content ul li::marker {
  color: var(--color-teal-50);
}

.fullImg_desktop {
  display: none;
}

.fullImg_mobile {
  width: 100%;
}

.fullImg_padding {
  padding-left: 1em;
  padding-right: 1em;
}

.infoCallout_container {
  padding: 1.125em 1.25em;
}

.infoCallout_graphic {
  position: relative;
  border: .0625em solid transparent;
  border-left: none;
  border-bottom: none;
}

.infoCallout_graphic:not(:empty)::after {
  content: "";
  display: var(--verticalBorderLineDisplay);
  position: absolute;
  border-right: 0.0625em solid var(--color-red-30);
  top: 0px;
  left: 0.0625em;
  width: 100%;
  min-height: 4.375em;
}

.infoCallout_graphic::before {
  content: "";
  height: 0.625em;
  width: 0.625em;
  position: absolute;
  left: 0px;
  top: -0.3125em;
  background-color: var(--hrBoxColor);
}

.infoCallout_graphic[blank] {
  display: none;
}

.infoCallout_content {
  display: flex;
  width: 100%;
  padding: 1.25em 1.25em 0px 0px;
}

.dosePanels_wrapper {
  display: flex;
  flex-wrap: wrap;
  width: 100%;
  margin-top: 2em;
  row-gap: 1.5em;
}

.dosePanels_heading {
  font-weight: var(--font-weight-medium);
  font-size: 1.125em;
}

.dosePanels_calloutText {
  margin-bottom: 0px;
  font-weight: var(--font-weight-bold);
  color: var(--color-black-70);
}

.dosePanels_icon {
  max-height: 2.1875em;
  width: auto;
  margin-right: 1.5625em;
}

.dosePanels_descWrap {
  margin-bottom: 1em;
}

.dosePanel_card {
  width: 100%;
  text-align: center;
  position: relative;
  row-gap: 1.5em;
  margin-bottom: 1.5em;
}

.dosePanel_card::after {
  position: absolute;
  content: "";
  bottom: -2.1875em;
  border-top: 0.625em solid var(--color-black-light);
  border-bottom: 0.625em solid var(--color-black-light);
  border-left: 0.625em solid var(--color-teal-70);
  transform: rotate(90deg);
}

.dosePanel_card:last-child::after {
  display: none;
}

.dosePanel_box {
  position: relative;
  background-color: var(--color-teal-10);
  border: 0.0625em solid var(--color-teal-70);
  color: var(--color-teal-50);
  padding: 1em 1.5em;
}

.dosePanel_container {
  width: 100%;
  position: relative;
}

.dosePanel_title {
  color: var(--color-black-70);
  font-size: 1.125em;
  font-weight: var(--font-weight-bold);
  margin-bottom: 0.75em;
}

.dosePanel_heading {
  font-weight: var(--font-weight-bold);
  font-size: 1.625em;
  margin-bottom: 0.5em;
}

.dosePanel_desc {
  font-weight: var(--font-weight-bold);
  text-transform: uppercase;
  margin-bottom: 0px;
}

.heading-teal {
  color: var(--color-teal-70);
}

.heading-gray {
  color: var(--color-gray-90);
}

.boxPanel_content .heading-large strong {
  font-size: 32px;
}

.heading-medium {
  font-size: 24px;
}

.heading-small {
  font-size: 22px;
  font-family: var(--font-family-headings);
  color: var(--color-blue-60);
}

.text-small {
  font-size: 13px;
}

.text-blue {
  color: var(--color-blue-60);
}

.text-lowercase {
  text-transform: lowercase;
}

.bullet-list {
  margin-left: 20px;
}

.cta-callout {
  align-items: center;
  border-style: solid;
  border-width: 0.625em 0 0;
  border-color: var(--border-color);
  display: flex;
  flex-direction: column;
  justify-content: flex-start;
  padding: 2.5em 1.5625em 0;
  border: none;
}

.cta-content {
  display: flex;
  flex-direction: column;
  align-items: center;
  margin-bottom: 1.875em;
}

.cta-icon {
  margin-bottom: 0.9375em;
  max-width: 4.0625em;
  height: 4.1875em;
}

.cta-text {
  text-align: center;
}

.cta-description p {
  font-weight: var(--font-weight-medium);
  margin-bottom: 0px;
  font-size: 1.125em;
}

.custom-sup-2 sup{
  vertical-align: unset;
  position: relative;
  top: -10px;
}

@media (min-width: 48em) {
  .boxPanel_content :where(h1, h2, h3, h4, h5, h6) {
    font-size: 1.375rem;
  }

  .boxed-panel-one.container {
    padding-right: 0;
  }

  .boxPanel_btnWrap {
    flex-direction: row;
    gap: 1.5em;
    flex-wrap: wrap;
  }

  .boxPanel_btn {
    width: fit-content;
  }

  .fullImg_desktop {
    display: block;
    width: 100%;
  }

  .fullImg_mobile {
    display: none;
  }

  .fullImg_padding {
    padding-right: 2.75em;
    padding-left: 2.75em;
  }

  .infoCallout_container {
    align-items: center;
  }

  .infoCallout_content {
    padding: 1.25em;
  }

  .dosePanels_wrapper {
    margin-bottom: 1.5em;
  }

  .dosePanels_heading {
    font-size: 1.375em;
  }

  .dosePanel_card {
    position: relative;
    margin-right: 2.625em;
    max-width: 16.5625em;
    margin-bottom: 0px;
  }

  .dosePanel_card::after {
    right: -1.5625em;
    bottom: 25%;
    transform: rotate(0deg);
  }

  .dosePanel_container {
    max-width: 16.5625em;
    position: relative;
    margin-right: 2.625em;
  }

  .dosePanel_box::after {
    transform: rotate(0deg);
    bottom: 36%;
    right: -1.75em;
  }

  .cta-callout {
    border-width: 0 0 0 0.625em;
    justify-content: flex-start;
    flex-direction: inherit;
    padding: 1.25em 0;
  }

  .cta-content {
    margin-left: 0;
    margin-bottom: 0;
    margin-right: auto;
    align-items: center;
    flex-direction: inherit;
  }

  .cta-icon {
    margin: -0.625em 1.875em 0 0;
  }

  .cta-text {
    text-align: unset;
    display: flex;
    flex-wrap: wrap;
  }

  .cta-description p {
    margin-bottom: 0px;
    margin-right: 0.3125em;
    display: flex;
    align-items: center;
  }

  .custom-sup-2 sup{
    vertical-align: super;
    position: static;
  }
}

@media (min-width: 62.0625em) {
  .fullImg_padding {
    padding-right: 6.375em;
    padding-left: 6.375em;
  }

  .infoCallout_container {
    padding: 1.25em 1.5625em;
    max-width: var(--maxWidth);
  }

  .infoCallout_content {
    align-items: center;
    padding: 1.25em;
  }

  .dosePanels_calloutText {
    font-size: 1.125em;
  }

  .dosePanels_icon {
    max-height: 2.8125em;
  }

  .cta-description p {
    font-size: 1.375em;
    line-height: 1.22;
  }

  .dosing_top_container {
    margin-top: 15px;
  }
}