.efficacy-page .standardPanel_content :where(h1) {
  margin-bottom: 0px;
}

.efficacy-page .standardPanel_content hr {
  border-top: 0.1875em solid var(--color-red-30);
  width: 100%;
  display: inline-block;
  margin: 10px 0px 0px;
}

.efficacy-page .anchor_anchor {
  scroll-margin-top: var(--scroll-margin);
  display: block;
}

.efficacy-page .fullWidthPromoWithList_toggle {
  margin-top: 1em;
  color: var(--color-teal-70);
  font-weight: var(--font-weight-semibold);
}

.efficacy-page .trialResultsPanel_description p {
  font-size: 1.125rem;
  margin-bottom: 1.25rem;
}

.efficacy-page .trialResultsPanel_description ul {
  margin-bottom: 1.25rem;
}

.efficacy-page .trialResultsPanel_description h5 {
  color: var(--color-gray-90);
}

.efficacy-page .trialResultsPanel_middleSection {
  display: flex;
  flex-direction: row;
  gap: 2.25em;
  margin: 1.5em 0px;
}

.efficacy-page .trialResultsPanel_graphImageLeft {
  width: 100%;
}

.efficacy-page .fullWidthPromoWithList_toggle:after {
  content: " +";
  margin-left: 0.25em;
}

.efficacy-page .fullWidthPromoWithList_toggle[aria-expanded="true"]:after {
  content: " -";
}

.efficacy-page .fullWidthPromoWithList_title {
  font-size: 1.125em;
  font-weight: var(--font-weight-medium);
  margin-bottom: 1em;
}

.efficacy-page .fullWidthPromoWithList_list__title {
  font-size: 1.125em;
  font-weight: var(--font-weight-bold);
}

.efficacy-page .fullWidthPromoWithList_container {
  --label-vertical-offset: 1.75em;
  --label-horizontal-offset: -1px;
}

.efficacy-page .fullWidthPromoWithList_container__inner {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  justify-content: space-between;
  position: relative;
  margin-top: 68px;
  padding: 1.5em 1em;
  background-color: var(--color-teal-10);
  border: 1px solid var(--color-blue-80);
}

.efficacy-page .fullWidthPromoWithList_label {
  position: absolute;
  z-index: var(--z-index-label);
  top: calc(var(--label-vertical-offset) * -1);
  left: var(--label-horizontal-offset);
  padding: 0.375em 0.5em;
  text-transform: uppercase;
  color: var(--color-white);
  font-family: var(--font-family-primary);
  font-size: 1.25em;
}

.efficacy-page .fullWidthPromoWithList_column > * {
  color: var(--color-black-90);
  font-size: 1em;
}

.efficacy-page .fullWidthPromoWithList_column + .fullWidthPromoWithList_column {
  margin-top: 1em;
  padding-top: 1em;
  border-top: 4px solid var(--color-red-30);
}

.efficacy-page .fullWidthPromoWithList_toggle {
  margin-top: 1em;
  color: var(--color-teal-70);
  font-weight: var(--font-weight-semibold);
}

.efficacy-page .fullWidthPromoWithList_button {
  margin-top: 1em;
}

.efficacy-page .fullWidthPromoWithList_collapsable__container {
  padding: 1.5em 1em;
  border-top: 0px;
}

.efficacy-page .fullWidthPromoWithList_image {
  margin: 1em 0px;
}

.efficacy-page .fullWidthPromoWithList_promo__text {
  margin-top: 1em;
}

.efficacy-page .fullWidthPromoWithList_button_container {
  display: flex;
  flex-direction: column;
  gap: 1rem;
}

.efficacy-page .fullWidthPromoWithList_full_width_button {
  width: 100%;
}

.efficacy-page .threeTabPanel_tabsContainer {
  display: flex;
  flex-direction: column;
  padding-bottom: 1.5em;
  margin-top: 1em;
}

.efficacy-page .threeTabPanel_singleTab {
  font-family: var(--font-family-headings);
  border-color: var(--color-gray-50);
  border-style: solid;
  border-width: 0.0625em 0.0625em 0.0625em 0.25em;
  font-size: 1em;
  font-weight: var(--font-weight-medium);
  text-align: left;
  color: var(--color-black-70);
  cursor: pointer;
  padding: 0.5rem 1rem;
}

.efficacy-page .threeTabPanel_selectedTab__c_Was {
  background: var(--color-white);
  border-left-color: var(--color-teal-70);
  color: var(--color-teal-70);
}

.efficacy-page .trialResultsPanel_panelTitle {
  font-size: 1.5em;
  font-weight: var(--font-weight-bold);
  margin-bottom: 0.5em;
}

.efficacy-page .trialResultsPanel_panelTitle.text-mb {
  margin-bottom: 20px;
}

.efficacy-page .trialResultsPanel_description p {
  font-size: 1.125rem;
  margin-bottom: 1.25rem;
}

.efficacy-page .trialResultsPanel_description ul {
  margin-bottom: 1.25rem;
}

.efficacy-page .trialResultsPanel_description h5 {
  color: var(--color-gray-90);
}

.efficacy-page .trialResultsPanel_middleSection {
  display: flex;
  flex-direction: row;
  gap: 2.25em;
  margin: 1.5em 0px;
}

.efficacy-page .trialResultsPanel_graphImageLeft {
  width: 100%;
}

.efficacy-page .resourcePanel2_boxContainer {
  display: flex;
  flex-direction: column;
  gap: 1rem;
  width: 100%;
  height: 100%;
}

.efficacy-page .threeTabPanel_tabsContainer {
  display: flex;
  flex-direction: column;
  padding-bottom: 1.5em;
  margin-top: 1em;
}

.efficacy-page .trialResultsPanel_eyebrow {
  font-size: 1.125em;
  font-weight: var(--font-weight-medium);
}

.efficacy-page .trialResultsPanel_description p {
  font-size: 1.125rem;
  margin-bottom: 1.25rem;
}

.efficacy-page .trialResultsPanel_description.description_lt p {
  line-height: 22.5px;
}

.efficacy-page .trialResultsPanel_description h5 {
  color: var(--color-gray-90);
}

.efficacy-page .trialResultsPanel_middleSection {
  display: flex;
  flex-direction: row;
  gap: 2.25em;
  margin: 1.5em 0px;
}

.efficacy-page .trialResultsPanel_graphImageLeft {
  width: 100%;
}

.efficacy-page .ctaCallout_ctaCallout {
  align-items: center;
  border-style: solid;
  border-width: 0.625em 0px 0px;
  border-color: var(--border-color);
  display: flex;
  flex-direction: column;
  justify-content: flex-start;
  padding: 2.5em 1.5625em 0px;
}

.efficacy-page .ctaCallout_ctaCalloutContent {
  display: flex;
  flex-direction: column;
  align-items: center;
  margin-bottom: 1.875em;
}

.efficacy-page .ctaCallout_ctaIcon {
  margin-bottom: 0.9375em;
  max-width: 4.0625em;
  height: 4.1875em;
}

.efficacy-page .ctaCallout_ctaCallout__text {
  text-align: center;
}

.efficacy-page .ctaCallout_ctaCallout__description p {
  font-weight: var(--font-weight-medium);
  margin-bottom: 0px;
  font-size: 1.125em;
  margin-bottom: 20px;
  line-height: 22.5px;
}

.efficacy-page .ctaCallout_ctaCallout {
  border: none;
}

.efficacy-page .fullWidthPromoWithList_image__button {
  display: none;
}

.dialog[data-reach-dialog-overlay] {
  z-index: var(--z-index-overlay);
  display: flex;
  align-items: center;
  justify-content: center;
  background-color: var(--color-black-transparent-80);
}

.dialog__content[data-reach-dialog-content] {
  width: 100%;
  background-color: initial;
  padding: 0px;
  margin: 0px;
}

[data-reach-dialog-overlay] {
  background: var(--color-black-54);
  position: fixed;
  top: 0;
  right: 0;
  bottom: 0;
  left: 0;
  overflow: auto;
}

[data-reach-dialog-content] {
  width: 50vw;
  margin: 10vh auto;
  background: var(--color-white);
  padding: 2rem;
  outline: none;
}

.efficacy-page .heading-eyebrow-teal {
  color: var(--color-teal-70);
}

.efficacy-page .small-text {
  font-size: 13px;
}

.efficacy-page .small-text.text-mb {
  line-height: 16.25px;
  margin-bottom: 13px;
}

.efficacy-page .flex-display {
  display: flex;
}

.efficacy-page .flex-margin-bottom {
  display: flex;
  margin-bottom: 3px;
}

.efficacy-page .small-spacer {
  width: 6.36px;
}

.efficacy-page .max-width-full {
  max-width: 100%;
}

.efficacy-page .max-width-two-thirds {
  max-width: 66.66%;
}

.efficacy-page .subgroup-heading-text {
  color: var(--color-black);
}

.siteMain > .container.padding-top-bottom {
  padding-top: 0px;
}

.efficacy-page .toggle-full-width {
  width: 100%;
  justify-content: left;
}

.efficacy-page .forest-plot-image {
  width: 985px;
  object-fit: contain;
  max-height: fit-content;
}

.efficacy-page .promo-background {
  background-image: url("/images/pages/efficacy/Asset-20.png");
  background-position-x: unset;
  background-position-y: 100%;
  background-size: 100% 100%;
  background-repeat: no-repeat;
  background-attachment: unset;
  background-origin: unset;
  background-clip: unset;
  background-color: unset;
  border: none;
  padding-bottom: 60px;
  padding-top: 60px;
}

.efficacy-page .group-heading {
  font-size: 18px;
}

.efficacy-page .list-style-unset {
  list-style-type: unset !important;
}

.efficacy-page .bold-text {
  font-weight: 700;
}

.efficacy-page .panel-heading-text {
  font-size: 18px;
  color: var(--color-black);
  font-weight: 400;
  line-height: 22.5px;
  font-family: var(--font-family-primary);
}

.efficacy-page .panel-heading-text-italic {
  font-size: 18px;
  font-style: normal;
  color: var(--color-black);
  font-weight: 700;
}

.efficacy-page .panel-font-size {
  font-size: 2em;
}

.efficacy-page .eyebrow-blue {
  color: var(--color-blue-60);
  font-family: var(--font-family-headings);
}

.efficacy-page .row-gap {
  row-gap: 1.25em;
  gap: 3.25em;
}

.efficacy-page .exploratory-heading {
  margin-top: 2rem;
  margin-bottom: 0.5em;
  font-weight: 500;
}

.efficacy-page .margin-bottom-half {
  margin-bottom: 0.5em;
}

.efficacy-page .margin-left-40 {
  margin-left: 40px;
}

.efficacy-page .list-style-dash {
  list-style-type: "- ";
}

.efficacy-page .small-text-bottom-margin {
  font-size: 13px;
  margin-bottom: 2.5rem;
}

.efficacy-page .small-text-bottom-margin.text-mb {
  line-height: 16.25px;
}

.efficacy-page .border-teal {
  --border-color: var(--color-teal-50);
}

.efficacy-page .isi-tray-top {
  top: unset;
}

.efficacy-page .dialog-overlay-style {
  width: 1px;
  height: 0px;
  padding: 0px;
  overflow: hidden;
  position: fixed;
  top: 1px;
  left: 1px;
}

.efficacy-page .group-heading-display {
  font-size: 18px;
  color: var(--color-black);
  font-weight: 400;
  display: block;
  font-family: var(--font-family-primary);
}

.efficacy-page .bullet_font {
  font-family: var(--font-family-primary);
}

.efficacy-page .bullet_font li {
  margin-bottom: 9px;
}

.efficacy-page .dialog-button-color {
  --color-close-button: var(--color-gray-10);
}

.efficacy-page .dialog-button-white {
  --color-close-button: var(--color-white);
}

.efficacy-page .screen-reader-text {
  border: 0px;
  clip: rect(0px, 0px, 0px, 0px);
  height: 1px;
  margin: -1px;
  overflow: hidden;
  padding: 0px;
  position: absolute;
  width: 1px;
  white-space: nowrap;
  overflow-wrap: normal;
}

.efficacy-page .header-style {
  font-size: 20px;
  color: var(--color-blue-60);
}

.efficacy-page .header-content {
  font-size: 16px;
  display: block;
}

.efficacy-page .indication-content {
  font-size: 16px;
}

.efficacy-page .exploratory-text {
  font-size: 18px;
  color: var(--color-black);
  font-weight: 400;
}

.efficacy-page .sup-style {
  vertical-align: top;
  display: inline-block;
  line-break: strict;
  position: relative;
  font-size: 0.7em;
  top: -0.5em;
}

.efficacy-page .margin-right-sm {
  margin-right: 0.22em;
}

.efficacy-page .line-height-lg {
  line-height: 1.8em;
}

.efficacy-page .sup-position {
  font-size: 1.4rem;
  top: -0.2em;
  position: relative;
}

.efficacy-page .font-size-15 {
  font-size: 15px;
}

.dialog.fullWidthPromoWithList_dialog {
  display: none;
}

.efficacy-page .standardPanel_content p a {
  text-decoration: none;
}

.efficacy-page .standardPanel_content p a:hover {
  text-decoration: underline;
}

@media (min-width: 48em) {
  .efficacy-page .fullWidthPromoWithList_list__title,
  .efficacy-page .fullWidthPromoWithList_title {
    font-size: 1.375em;
  }

  .efficacy-page .fullWidthPromoWithList_container {
    --label-vertical-offset: 0;
    --label-horizontal-offset: 1.8125em;
  }

  .efficacy-page .fullWidthPromoWithList_container__inner {
    margin-left: var(--label-horizontal-offset);
    gap: 0px 3em;
    justify-content: center;
    margin-top: 20px;
  }

  .efficacy-page .fullWidthPromoWithList_label {
    top: 1.3125em;
    left: calc(var(--label-horizontal-offset) * -1);
    max-width: 8.25em;
    font-size: 1em;
  }

  .efficacy-page .fullWidthPromoWithList_columns {
    display: flex;
    gap: 0px 1em;
  }

  .efficacy-page .fullWidthPromoWithList_column {
    flex: 0 0 calc(50% - 0.5em);
  }

  .efficacy-page
    .fullWidthPromoWithList_column
    + .fullWidthPromoWithList_column {
    border-top: 0px;
    border-left: 3px solid var(--color-red-30);
    margin: 0px;
    padding: 0px 0px 0px 1em;
  }

  .efficacy-page .fullWidthPromoWithList_collapsable__container {
    margin-left: var(--label-horizontal-offset);
  }

  .efficacy-page .threeTabPanel_tabsContainer {
    display: block;
    margin-top: 2em;
  }

  .efficacy-page .threeTabPanel_singleTab {
    width: calc(100% / var(--tabsLength));
    border-width: 0.0625em 0.0625em 0px;
    font-size: 1.75vw;
  }

  .efficacy-page .threeTabPanel_selectedTab__c_Was {
    color: var(--color-teal-70);
    border-radius: 0.25em 0.25em 0px 0px;
    border-top-color: var(--color-teal-70);
    border-left-color: var(--color-gray-50);
    border-top-width: 0.25em;
    position: relative;
    border-bottom: none;
  }

  .efficacy-page .trialResultsPanel_panelTitle {
    font-size: 2em;
  }

  .efficacy-page .threeTabPanel_tabsContainer {
    display: block;
    margin-top: 2em;
  }

  .efficacy-page .trialResultsPanel_eyebrow {
    font-size: 1.375em;
  }

  .efficacy-page .ctaCallout_ctaCallout {
    border-width: 0px 0px 0px 0.625em;
    justify-content: flex-start;
    flex-direction: inherit;
    padding: 1.25em 0px;
  }

  .efficacy-page .ctaCallout_ctaCalloutContent {
    margin-left: 0px;
    margin-bottom: 0px;
    margin-right: auto;
    align-items: center;
    flex-direction: inherit;
  }

  .efficacy-page .ctaCallout_ctaIcon {
    margin: -0.625em 1.875em 0px 0px;
  }

  .efficacy-page .ctaCallout_ctaCallout__text {
    text-align: unset;
  }

  .efficacy-page .ctaCallout_ctaCallout__description p,
  .ctaCallout_ctaCallout__link {
    margin-bottom: 0px;
    margin-right: 0.3125em;
    display: flex;
    align-items: center;
  }

  .efficacy-page .ctaCallout_ctaCallout__text {
    display: flex;
    flex-wrap: wrap;
  }

  .efficacy-page .description_lt ul.Bullet.font-size li::marker,
  .efficacy-page .description_lt ul.BulletColumn.font-size li::marker,
  .efficacy-page .description_lt ul.BulletIndent.font-size li::marker,
  .efficacy-page .description_lt ul.listUnordered.font-size li::marker {
    font-size: 27.5px;
  }

  .efficacy-page .fullWidthPromoWithList_image__button {
    display: none;
  }

  .dialog__content[data-reach-dialog-content] {
    width: 60%;
  }

  .efficacy-page .title-align-left {
    position: relative;
    left: -13px;
  }

  .efficacy-page .group-heading-display {
    font-size: 16px;
    line-height: 20px;
  }

  .efficacy-page .bullet_font li {
    margin-bottom: 8px;
    line-height: 20px;
  }

  .efficacy-page ul.Bullet.bullet_font li::marker {
    font-size: 20px;
  }
}

@media (min-width: 62.0625em) {
  .efficacy-page .fullWidthPromoWithList_column > * {
    font-size: 1.125em;
  }

  .efficacy-page .fullWidthPromoWithList_column p {
    margin-bottom: 18px;
  }

  .efficacy-page .fullWidthPromoWithList_column p span.group-heading {
    line-height: 22.5px;
  }

  .efficacy-page .fullWidthPromoWithList_column ul li {
    font-size: 16px;
  }

  .efficacy-page .fullWidthPromoWithList_container__image {
    position: relative;
    width: 50%;
    margin: auto;
  }

  .efficacy-page .fullWidthPromoWithList_image__button {
    position: absolute;
    bottom: 0px;
    right: 0px;
  }

  .efficacy-page .fullWidthPromoWithList_icon__zoom {
    width: 1.5625em;
    height: 1.5625em;
  }

  .efficacy-page .fullWidthPromoWithList_column {
    padding-left: 8em;
  }

  .efficacy-page
    .fullWidthPromoWithList_column
    + .fullWidthPromoWithList_column {
    padding: 0px 8em 0px 3em;
  }

  .efficacy-page .threeTabPanel_tabsContainer {
    padding-bottom: 2.5em;
  }

  .efficacy-page .threeTabPanel_singleTab {
    text-align: center;
    font-size: 1.35vw;
  }

  .efficacy-page .resourcePanel2_boxContainer {
    flex: 0 0 48%;
    width: 48%;
  }

  .efficacy-page .threeTabPanel_tabsContainer {
    padding-bottom: 2.5em;
  }

  .efficacy-page .ctaCallout_ctaCallout__description p,
  .efficacy-page .ctaCallout_ctaCallout__link {
    font-size: 1.375em;
  }

  .efficacy-page .ctaCallout_ctaCallout__description p {
    line-height: 1.22;
  }

  .efficacy-page .fullWidthPromoWithList_image__button {
    display: unset;
  }

  .fullWidthPromoWithList_list__title.font-size {
    font-size: 22px;
  }

  .fullWidthPromoWithList_list__title.font-size ul.Bullet li::marker {
    font-size: 22.5px;
  }

  .efficacy-page .title-align-left {
    position: relative;
    left: -16px;
  }

  .dialog.fullWidthPromoWithList_dialog {
    display: flex;
  }

  .fullWidthPromoWithList_dialog__content[data-reach-dialog-content] {
    width: 70%;
    padding: 2em;
    margin-top: 1.75em;
    background-color: var(--color-white);
  }

  .fullWidthPromoWithList_dialog__button {
    float: right;
  }

  .fullWidthPromoWithList_dialog__buttonSecondary {
    display: block;
    margin: 2em auto 0px;
  }
  
  .bullet-points-display {
    font-size: 16px;
    color: #000;
    font-weight: 400;
    display: block;
    line-height: 20px;
  }

  ul.Bullet li.list-style-type {
    line-height: 20px;
    margin-bottom: 8px;
  }

  ul.Bullet li.list-style-type:last-child {
    margin-bottom: 0px;
  }
}